Anti-Müllerian hormone is a 140 kDa glycoprotein that is produced during normal embryogenesis by the Sertoli cells of the embryonic testis, causes the involution of the Müllerian duct, and inhibits female gonadogenesis by inducing apoptosis of target gonadal cells. It belongs to the transforming growth factor-β super family. AMH causes apoptosis of specific Anti-Müllerian inhibiting substance (MIS) receptor-bearing cells, while having no effect on cells without receptors. AMH is also expressed in granulosa cells of preantral and small antral follicles in the ovary, and AMH inhibits recruitment of primordial follicles into the pool of growing follicles, and decreases responsiveness of growing follicles to FSH.

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Acharya M, Burke JM, Anshworth AJ, Rorie R. Relationship of Anti-Mullerian Hormone to Reproductive Traits in Katahdin Ewes Bred in Late Spring or Fall. Advances in Reproductive Sciences January 2020 08(01):48-56. DOI: 10.4236/arsci.2020.81005

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Hanlon D, Hllinshead F, Evans M. Anti-Mullerian Hormone (AMH) as a potential predective marker of fertility in mares. unpublished

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Kaps M, Okada CTC, Gautier CM, Aurich J, Aurich C. . Deslorelin Slow-Release Implants Delay Ovulation and Increase Plasma AMH Concentration and Small Antral Follicles in Haflinger Mares. Animals (Basel). 2021 May 28;11(6):1600.

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Kumar A, Kalra B, Patel A, Shah S. New Sensitive Anti-Müllerian Hormone (AMH) ELISAs for Non-Human Primate, Rodent, Equine, Bovine, Canine and Other Species. Poster session presented at: American Association for Clinical Chemistry; 2013; Jul 30-Aug 1; Houston, TX.

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Renata Cristina Uliani. Disseration: Efeito da Ovariectomia e Idade Sobre as Concentrações Séricas de Hormônio Anti-Mülleriano em Éguas. [Dissertation, 2016]. Universidade Estadual Paulista “Júlio de Mesquita Filho” (Brazil), Faculdade de Medicina Veterinária e Zootecnia”.

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Scarlet D, Kuhl J, Wulf M, Ille N, Aurich C. Antral Follicle Count of 2-Year-Old Mares is Highly Correlated with Anti-Müllerian Hormone Concentrations at 24 to 28 Weeks of Age. Reprod Fertil Dev. 2016 Jan;29(1):168-169.

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Scarlet D, Wulf M, Kuhl J, Köhne M, Ille N, Conley AJ, Aurich C. Anti-Müllerian hormone profiling in prepubertal horses and its relationship with gonadal function. Theriogenology. 2018 Sep 1;117:72-77.

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Uliani RC, Conley AJ, Corbin CJ, Friso AM, Maciel LFS, Alvarenga MA. . Anti-Müllerian hormone and ovarian aging in mares. J Endocrinol . 2019 Feb 1;240(2):147-156. doi: 10.1530/JOE-18-0391.

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Uliani RC, Conley AJ, Corbin CJ, Friso AM, Maciel LFS, Alvarenga MA. . Experimental validation of anti-Mullerian hormonae as a quantitative marker of ovarian follicular reserve using unilateral ovariectomy in mares. Clinical Theriogenology 2017 Vol.9 No.3 pp.462

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